Targeted treatment for bacterial infections: prospects for pathogen-specific antibiotics coupled with rapid diagnostics

T Maxson, DA Mitchell - Tetrahedron, 2016 - Elsevier
The advent of antibiotics in the early twentieth century catalyzed a medical revolution,
drastically reducing mortality due to bacterial infections. Along with numerous other
advances in healthcare, such as vaccines and improved sanitation, antibiotics have
contributed to an extension in the average life expectancy in the USA from 59.7 years in
1930 to 78.7 years in 2010. 1 Antibiotics are a critical component of a number of modern
medical procedures, including many surgeries and transplants, as the rate of severe …